Article

Somatic maintenance impacts the evolution of mutation rate

2017-08-25

Abstract excerpt

The evolution of multi-cellular animals has produced a conspicuous trend toward increased body size. This trend has introduced at least two novel problems: an elevated risk of somatic disorders, such as cancer, and declining evolvability due to reduced population size, lower reproduction rate and extended generation time. Low population size is widely recognized to explain the high mutation rates in animals by lim...

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Identifiers and source

Literature Corpus work: f10b013e-06b9-5ac0-9349-7703a3602a06
DOI: 10.1101/181065

Open publication

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