Article
The Evolutionary Interplay of Somatic and Germline Mutation Rates.
Annual review of biomedical data science - 1 Aug 2024
Beichman Annabel C, Zhu Luke, Harris Kelley
Abstract excerpt
Novel sequencing technologies are making it increasingly possible to measure the mutation rates of somatic cell lineages. Accurate germline mutation rate measurement technologies have also been available for a decade, making it possible to assess how this fundamental evolutionary parameter varies across the tree of life. Here, we review some classical theories about germline and somatic mutation rate evolution...
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