Article

What sets the mutation rate of a cell type in an animal species?

2025-12-22

Abstract excerpt

<h4>ABSTRACT</h4> Germline mutation rates per generation are strikingly similar across animals, despite vast differences in life histories. Analogously, in at least one somatic cell type, mutation rates at the end of lifespan are comparable across mammals. These observations point to a key role for natural selection in shaping mutation rates. In this essay, we summarize the patterns identified to date and outline...

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Literature Corpus work: 781805c3-d3c1-52ac-adb0-1f4dc191b431
DOI: 10.64898/2025.12.19.695482

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