Article

Expression of active human epidermal growth factor (hEGF) in tobacco plants by integrative and non-integrative systems

2004-01-01

Abstract excerpt

Human epidermal growth factor (hEGF) was expressed in Nicotiana plants using integrative and non-integrative systems. Nuclear transformation was carried out using genetic constructs that allow hEGF accumulation into the cytoplasmic or apoplastic spaces. Protein level did not exceed 0.00001% of total soluble protein in the cytoplasm, but reached values of up to 0.11% when hEGF was targeted to the apoplast. In addit...

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Literature Corpus work: 3498e8fc-73c2-56ea-856b-6d2a54e85260
DOI: 10.1023/b:molb.0000012329.74067.ca

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