Article

Plant-derived recombinant human insulin-like growth factor precursor prohormone IGF-1B caused differentiation of human neuroblastoma cell lines SH-SY5Y

2003-08-01

Abstract excerpt

The potential of plant expression systems to produce functional recombinant proteins was used to produce human prohormone insulin-like growth factor-1B (pro-IGF-1B). Insulin-like growth factor-1 (IGF-1) plays a role in normal growth, development and cell division. The analysis of IGF-1 cDNAs predicted two prohormone precursors (pro-IGF-1A and pro-IGF-1B) with distinct C-terminal E domains. The functions of these p...

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Literature Corpus work: 4d5e0afe-d37d-56fe-a356-fdfba66e65f0
DOI: 10.1023/a:1025480316926

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