Back to search

Article

Circulating tumor DNA precision oncology enables effective and sensitive molecular diagnostics and actionable target detection in pediatric solid tumors - the INFORM experience

2026-01-22

Abstract excerpt

Pediatric solid high-risk malignancies mostly lack established molecular biomarkers for early detection, minimal residual disease assessment, or treatment monitoring. Challenges include small patient numbers, limited sample volumes, low tumor mutational burden, and few recurrent alterations. Within the prospective multicenter pediatric precision oncology program INFORM, we collected liquid biopsies from 130 pediat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1fa581de-a741-54d7-b6ef-9de0349a3dea
DOI
10.64898/2026.01.19.26344140
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Circulating tumor DNA precision oncology enables effective and sensitive molecular diagnostics and actionable target detection in pediatric solid tumors - the INFORM experienceDOI 10.64898/2026.01.19.26344140
Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid TumorsSemantic proximity
The Use of Circulating Tumor DNA Assays and Liquid Biopsies in Pediatric Brain Tumors: A ReviewSemantic proximity
Circulating cell-free tumor DNA analysis in pediatric cancersSemantic proximity
Molecular profiling of 888 pediatric tumors informs future precision trials and data-sharing initiatives in pediatric cancer.Semantic proximity
Molecular profiling for precision cancer therapiesSemantic proximity
Genomic profiling of circulating tumor DNA for childhood cancers.Semantic proximity
A clinician's handbook for using ctDNA throughout the patient journey.Semantic proximity
Genomics-Driven Precision Medicine in Pediatric Solid TumorsSemantic proximity
Liquid biopsy detection of genomic alterations in pediatric brain tumors from cell-free DNA in peripheral blood, CSF, and urine.Semantic proximity
Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden.Semantic proximity
Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNASemantic proximity
Precision Medicine in Children and Young Adults with Hematologic Malignancies and Blood Disorders: The Columbia University ExperienceSemantic proximity
Select a neighboring publication to make it the new centre.