Article

Computational prediction and characterization of cell-type-specific and shared binding sites

2022-05-08

Abstract excerpt

<h4>ABSTRACT</h4> Cell-type-specific gene expression is maintained in large part by transcription factors (TFs) selectively binding to distinct sets of sites in different cell types. Recent research works have provided evidence that such cell-type-specific binding is determined by TF’s intrinsic sequence preferences, cooperative interactions with cofactors, cell-type-specific chromatin landscapes, and 3D chromati...

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Literature Corpus work: f03fe3d2-8f3a-570f-a358-92aa142de7d1
DOI: 10.1101/2022.05.06.490975

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