Article
Upregulated PD-1 Signaling is an Important Antagonist to Glomerular Health in Aged Kidneys
2021-10-26
Abstract excerpt
<h4>ABSTRACT</h4> Kidney aging and its contribution to disease and its underlying mechanisms are not well understood. With an aging population, kidney health becomes an important medical and socioeconomic factor. We previously showed that podocytes isolated from aged mice exhibit increased expression of Programed Cell Death Protein 1 (PD-1) surface receptor and its two ligands (PD-L1, PD-L2). PDCD1 transcript in...
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Identifiers and source
- Literature Corpus work
- e919c3d5-a6bc-574f-8749-9639a21c44ac
- DOI
- 10.1101/2021.10.26.466006