Article
Ovarian carcinomas: at least five different diseases with distinct histological features and molecular genetics.
Human pathology - 1 Oct 2018
Prat Jaime, D'Angelo Emanuela, Espinosa Iñigo
Abstract excerpt
Based on histopathology and molecular genetics, ovarian carcinomas are divided into five main types: high-grade serous (70%), endometrioid (10%), clear cell (10%), mucinous (3%), and low-grade serous (<5%) carcinomas. These tumors, which account for over 95% of cases, represent distinct diseases with different prognoses and treatments. TP53 mutations are identified in almost all (96%) high-grade serous carcinomas...
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