Article
Diverse molecular pathways in ovarian cancer and their clinical significance.
Maturitas - 20 Mar 2009
Ricciardelli Carmela, Oehler Martin K
Abstract excerpt
The origin of epithelial ovarian cancer remains unknown. It is believed to develop from ovarian surface epithelium, post-ovulatory inclusion cysts, endometriosis and more recently the fimbrial end of the fallopian tube. Molecular evidence suggests that ovarian cancer may progress both through a step-wise mutation process (low-grade pathway, type I), and a separate pathway with high genetic instability leading to...
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