Article

Fingolimod alters intrathecal B cell maturation in multiple sclerosis patients

2020-04-20

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: B cells are postulated to play multiple roles in the pathogenesis of multiple sclerosis (MS) including pathogenic antibody production, antigen-presentation and pro-inflammatory cytokine secretion. Natalizumab and fingolimod are effective MS therapies that disrupt lymphocyte migration but exert differential effects on B cell maturation and trafficking. Herein, we...

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Literature Corpus work: f02bf5ca-edfb-54b5-97d6-e0f795c0351b
DOI: 10.21203/rs.3.rs-23388/v1

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