Article

Selective emergence of antibody-secreting cells in the multiple sclerosis brain

2022-07-19

Abstract excerpt

<h4>Background: </h4> Although distinct brain-homing B cells have been identified in multiple sclerosis (MS), it is unknown how these further evolve to contribute to local pathology. In this study, we explored B-cell maturation in the central nervous system (CNS) of MS and control brain donors and determined their association with immunoglobulin (Ig) production, T-cell presence and lesion formation. <h4>Methods: <...

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Literature Corpus work: c204d37b-b664-5dcf-8830-0b0fbb4b984e
DOI: 10.21203/rs.3.rs-1857967/v1

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