Article
Natalizumab effects on immune cell responses in multiple sclerosis.
Annals of neurology - 1 May 2006
Niino Masaaki, Bodner Caroline, Simard Marie-Lune, Alatab Sudabeh, Gano Dawn, Kim Ho Jin, Trigueiro Manuela, Racicot Denise, Guérette Christine, Antel Jack P, Fournier Alyson, Grand'Maison Francois, Bar-Or Amit
Abstract excerpt
OBJECTIVE: Our objective was to study in vivo biological effects of natalizumab on immune cell phenotype and function in multiple sclerosis (MS) patients. METHODS: Blood was obtained before and after serial monthly natalizumab infusions to track functional expression of VLA-4 and migratory capaci...
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