Article

Observation of notable therapeutic response in a patient with systemic juvenile xanthogranuloma with KIF5B-ALK fusion

2024-01-31

Abstract excerpt

We report the case of a 1-year-old male patient with systemic juvenile xanthogranuloma in whom central nervous system lesions caused developmental retardation, spasticity and clonus of the lower extremities. He needed tube feeding and experienced severe bronchitis and generalised convulsive seizure. KIF5B-ALK fusion was identified in the cutaneous lesion, and he was administered alectinib, an ALK inhibitor. Two mo...

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Literature Corpus work: f02ad131-0222-59b0-8d66-ded69c62ebb8
DOI: 10.22541/au.170666131.10816153/v1

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