Article

Dabrafenib as a Therapeutic Option for Chemotherapy-Refractory pediatric Juvenile Xanthogranuloma: A Case Report

2025-08-16

Abstract excerpt

<h4>Background: </h4> Juvenile xanthogranuloma (JXG) is a rare non-Langerhans cell histiocytosis that typically presents as self-limiting cutaneous lesions in infants and young children. However, systemic involvement can lead to severe organ dysfunction and poses significant therapeutic challenges. Case presentation: We report a case of chemotherapy-refractory, multisystem JXG harboring BRAF V600E mutation in a 28...

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Literature Corpus work: f22676c5-5b83-5bba-8fa1-adb0a1331127
DOI: 10.22541/au.175537804.43355121/v1

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