Article

Concordance and incongruence in preclinical anxiety models: systematic review and meta-analyses

2015-06-10

Abstract excerpt

Rodent defense behavior assays have been widely used as preclinical models of anxiety to study possibly therapeutic anxiety-reducing interventions. However, some proposed anxiety-modulating factors—genes, drugs and stressors—have had discordant effects across different studies. To reconcile the effect sizes of purported anxiety factors, we conducted systematic review and meta-analyses of the literature on ten anxi...

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Literature Corpus work: f012fd4f-1307-5161-b451-2c5d7bbcf3cd
DOI: 10.1101/020701

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