Article
Experimental models of anxiety for drug discovery and brain research.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Hart Peter C, Bergner Carisa L, Smolinsky Amanda N, Dufour Brett D, Egan Rupert J, Laporte Justin L, Kalueff Allan V
Abstract excerpt
Animal models have been vital to recent advances in experimental neuroscience, including the modeling of common human brain disorders such as anxiety, depression, and schizophrenia. As mice express robust anxiety-like behaviors when exposed to stressors (e.g., novelty, bright light, or social confrontation), these phenotypes have clear utility in testing the effects of psychotropic drugs. Of specific interest is...
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