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Article

Construction and validation of a colon cancer prognostic model based on tumor mutation burden-related genes.

Scientific reports - 4 Feb 2024

Zou Daoyang, Xu Tianwen

Abstract excerpt

Currently, immunotherapy has entered the clinical diagnosis and treatment guidelines for colon cancer, but existing immunotherapy markers cannot predict the effectiveness of immunotherapy well. This study utilized the TCGA-COAD queue to perform differential gene analysis on high and low-mutation burden samples, and screen differentially expressed genes (DEGs). To explore new molecular markers or predictive models...

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Identifiers

PMID: 38311637
DOI: 10.1038/s41598-024-53257-z
PMCID: PMC10838917

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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