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miRNA-Based Signature Associated With Tumor Mutational Burden in Colon Adenocarcinoma

23 Jun 2021

Abstract excerpt

Colon adenocarcinoma (COAD) is one of the most common malignant tumors. Tumor mutation burden (TMB) has become an independent biomarker for predicting the response to immune checkpoint inhibitors (ICIs). miRNAs play an important role in cancer-related immune regulation. However, the relationship between miRNA expression and TMB in COAD remains unclear. Therefore, the transcriptome profiling data, clinical data,...

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PMID: 34262855
DOI: 10.3389/fonc.2021.634841

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