Article
Cardiomyogenesis in the adult human heart.
Circulation research - 23 Jul 2010
Kajstura Jan, Urbanek Konrad, Perl Shira, Hosoda Toru, Zheng Hanqiao, Ogórek Barbara, Ferreira-Martins João, Goichberg Polina, Rondon-Clavo Carlos, Sanada Fumihiro, D'Amario Domenico, Rota Marcello, Del Monte Federica, Orlic Donald, Tisdale John, Leri Annarosa, Anversa Piero
Abstract excerpt
RATIONALE: The ability of the human heart to regenerate large quantities of myocytes remains controversial, and the extent of myocyte renewal claimed by different laboratories varies from none to nearly 20% per year. OBJECTIVE: To address this issue, we examined the percentage of myocytes, endothelial cells, and fibroblasts labeled by iododeoxyuridine in postmortem samples obtained from cancer patients who...
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