Article

Identification of Novel Cryptic and Classical Clades in <i>Clostridioides difficile</i>

2025-08-01

Abstract excerpt

Clostridioides difficile is a major cause of nosocomial infections and antimicrobial-associated diarrhea, with significant global health implications. While five classical clades (C1 to C5) have traditionally encompassed most pathogenic strains, recent genomic studies have uncovered several highly divergent cryptic clades (C-I to C-V), suggesting greater taxonomic and evolutionary complexity. In this study, we per...

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Literature Corpus work: ef9c2432-2ffd-5489-9c24-bb0dc78ce709
DOI: 10.1101/2025.08.01.668003

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