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Article

Homologous Recombination in Clostridioides difficile Mediates Diversification of Cell Surface Features and Transport Systems.

mSphere - 18 Nov 2020

Steinberg Hannah D, Snitkin Evan S

Abstract excerpt

Illness caused by the pathogen Clostridioides difficile is widespread and can range in severity from mild diarrhea to sepsis and death. Strains of C. difficile isolated from human infections exhibit great genetic diversity, leading to the hypothesis that the genetic background of the infecting strain at least partially determines a patient's clinical course. However, although certain strains of C. difficile have...

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Identifiers

PMID: 33208516
DOI: 10.1128/mSphere.00799-20
PMCID: PMC7677006

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