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IL-17-producing CD8 <sup>+</sup> T cells differ in phenotype, metabolic profile and cytokine production to their CD4 <sup>+</sup> Th17 counterparts

2026-01-25

Abstract excerpt

Th17 cells (CD4 + T cells producing IL-17) are important for clearance of fungal infections and play a critical role in the development and exacerbation of numerous autoimmune diseases. Their differentiation, signalling pathways, cytokine production and metabolism are now well-characterised. As well as CD4 + T cells, CD8 + cells also produce IL-17 family members, and these have been named Tc17 cells. However, m...

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Literature Corpus work
0e30d453-fa0a-55b8-8a80-3304e082e15a
DOI
10.64898/2026.01.25.701586
Open publication

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IL-17-producing CD8 <sup>+</sup> T cells differ in phenotype, metabolic profile and cytokine production to their CD4 <sup>+</sup> Th17 counterpartsDOI 10.64898/2026.01.25.701586
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