Article

IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic Trypanosoma brucei infection

2023-06-08

Abstract excerpt

<title>Abstract</title> In the skin, <italic>Trypanosoma brucei</italic> colonises the subcutaneous white adipose tissue (scWAT) and harbours a pool of parasites that are proposed to be competent for forward transmission. The interaction between parasites, adipose tissue, and the local immune system is likely to drive the adipose tissue wasting and weight loss observed in cattle and humans infected with <itali...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 590f30cc-98fd-5944-ad5a-23c2d9346357
DOI: 10.21203/rs.3.rs-2986484/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic Trypanosoma brucei infectionDOI 10.21203/rs.3.rs-2986484/v1Read

IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic Trypanosoma brucei infectionSemantic proximity Read

IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infectionSemantic proximity Read

Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model.Semantic proximity Read

Deciphering visceral adipose tissue regulatory T cells: Key contributors to metabolic healthSemantic proximity Read

Rapid adipose tissue expansion triggers proliferation of memory adipose tissue T cells and accumulation of novel T helper 2 (Th2) regulatory cellsSemantic proximity Read

IL-17-producing CD8 + T cells differ in phenotype, metabolic profile and cytokine production to their CD4 + Th17 counterpartsSemantic proximity Read

Borrelia Burgdorferi binds Serum Amyloid A and Modulates Subcutaneous Adipose Tissue Immune SignalingSemantic proximity Read

Immunological liver-skin axis: a systemic Vγ4 + γδT17 cell response links psoriasis-like inflammation and MASLDSemantic proximity Read

Thinking outside the blood: Perspectives on tissue-resident Trypanosoma bruceiSemantic proximity Read

A lipid droplet triacylglycerol lipase governs neutral lipids mobilization and differentiation of Trypanosoma bruceiSemantic proximity Read

Functional genomics of trypanotolerant and trypanosusceptible cattle infected with Trypanosoma congolense across multiple time points and tissuesSemantic proximity Read

Adipose stem cells control obesity-induced T cell infiltration into adipose tissueSemantic proximity Read