Article

Structure of an endogenous mycobacterial MCE lipid transporter

2022-12-08

Abstract excerpt

To replicate inside human macrophages and cause the disease tuberculosis, Mycobacterium tuberculosis ( Mtb ) must scavenge a variety of nutrients from the host 1,2 . The Mammalian Cell Entry (MCE) proteins are important virulence factors in Mtb 1,3 , where they are encoded in large gene clusters and have been implicated in the transport of fatty acids 4–7 and cholesterol 1,4,8 across the impermeable mycobact...

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Literature Corpus work: ef881782-f7bc-542e-bccf-952619f03bea
DOI: 10.1101/2022.12.08.519548

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