Article

Insight into the structure and interactions of the <i>M. tuberculosis</i> Mce-associated membrane proteins Mam1A-1D

2025-03-26

Abstract excerpt

Tuberculosis (TB) is a major infectious disease caused by Mycobacterium tuberculosis (Mtb), leading to more than a million human deaths every year. Mammalian cell entry complexes (Mce1-4) play an essential role in the survival of Mtb during the latent stage by mediating the import of lipids, including fatty acids and cholesterol, from the host. The proper functioning of Mce-complexes requires additional proteins...

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Literature Corpus work: bbc8d140-0d9c-5f68-b73f-bc6b71fe0192
DOI: 10.1101/2025.03.26.645568

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