An orphaned Mce-associated membrane protein of Mycobacterium tuberculosis is a virulence factor that stabilizes Mce transporters.

doi:10.1111/mmi.13303

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Article

An orphaned Mce-associated membrane protein of Mycobacterium tuberculosis is a virulence factor that stabilizes Mce transporters.

Molecular microbiology - 1 Apr 2016

Perkowski Ellen Foot, Miller Brittany K, McCann Jessica R, Sullivan Jonathan Tabb, Malik Seidu, Allen Irving Coy, Godfrey Virginia, Hayden Jennifer D, Braunstein Miriam

Abstract excerpt

Mycobacterium tuberculosis proteins that are exported out of the bacterial cytoplasm are ideally positioned to be virulence factors; however, the functions of individual exported proteins remain largely unknown. Previous studies identified Rv0199 as an exported membrane protein of unknown function. Here, we characterized the role of Rv0199 in M. tuberculosis virulence using an aerosol model of murine infection....

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Identifiers

PMID: 26712165
DOI: 10.1111/mmi.13303
PMCID: PMC5028898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.