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<i>Tbx1</i> , a 22q11.2-encoded gene, is a link between alterations in fimbria myelination and cognitive speed in mice

2021-03-30

Abstract excerpt

Copy number variants (CNVs) have provided a reliable entry point to identify structural correlates of atypical cognitive development. Hemizygous deletion of human chromosome 22q11.2 is associated with impaired cognitive function; however, the mechanisms by which numerous genes encoded in this CNV contribute to cognitive deficits via diverse structural alterations in the brain remain unclear. This study aimed to de...

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Literature Corpus work
ef6be142-6265-558c-9f62-72ba10e1dd99
DOI
10.1101/2021.03.29.437581
Open publication

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<i>Tbx1</i> , a 22q11.2-encoded gene, is a link between alterations in fimbria myelination and cognitive speed in miceDOI 10.1101/2021.03.29.437581
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