Article

DNA Methylation-Based Deconvolution Study of Glioblastoma Heterogeneity and Cell Types Associated with Patient Survival

2025-06-09

Abstract excerpt

<title>Abstract</title> <p>Background: IDH-wildtype glioblastoma (GBM) is an aggressive, heterogeneous brain tumor with limited treatment options. This study tries to improve our understanding of GBM by applying DNA methylation-based deconvolution to define its cellular composition and its association with patient outcomes. <h4>Methods:</h4> We generated oligodendroglial precursor cells at various developmental...

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Literature Corpus work: e8693c4f-103d-5d74-8949-34282e9c9b48
DOI: 10.21203/rs.3.rs-6743395/v1

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