Article

RANKL signaling sustains primary tumor growth in genetically engineered mouse models of lung adenocarcinoma

2017-05-26

Abstract excerpt

<h4>Summary</h4> <h4>Hypothesis</h4> Non-small cell lung cancer (NSCLC) is the leading cause of cancer mortality. Recent retrospective clinical analyses suggest that blocking the receptor activator of NF-κB (RANK) signaling pathway inhibits the growth of NSCLC and might represent a new treatment strategy. <h4>Methods</h4> RANK and RANKL expression in human lung adenocarcinoma was interrogated from publicly ava...

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Literature Corpus work: eec23124-8502-53f2-84a8-c13cfbce78f3
DOI: 10.1101/142620

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