Article

<i>miR-200</i> deficiency promotes lung cancer metastasis by activating cancer-associated fibroblasts

2020-09-03

Abstract excerpt

Lung adenocarcinoma, the most prevalent lung cancer subtype, is characterized by its high propensity to metastasize. Despite the importance of metastasis in lung cancer mortality, its underlying cellular and molecular mechanisms remain largely elusive. Here, we identified miR-200 miRNAs as potent suppressors for lung adenocarcinoma metastasis. miR-200 expression is specifically repressed in mouse metastatic lung...

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Literature Corpus work: 85cec6b1-2b47-51fe-9981-0db72f6911b6
DOI: 10.1101/2020.09.02.276550

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