Article

FTO-mediated cytoplasmic m <sup>6</sup> A <sub>m</sub> demethylation adjusts stem-like properties in colorectal cancer cell

2020-01-09

Abstract excerpt

<h4>ABSTRACT</h4> Cancer stem cells (CSCs) are a small but critical cell population for cancer biology since they display inherent resistance to standard therapies and give rise to metastases. Despite accruing evidence establishing a link between deregulation of epitranscriptome-related players and tumorigenic process, the role of messenger RNA (mRNA) modifications dynamic in the regulation of CSC properties rema...

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Literature Corpus work: eea9ef88-5d24-5343-b385-3967aafe5f02
DOI: 10.1101/2020.01.09.899724

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