Article

Simulating Metabolic Pathways to Enhance Interpretations of Metabolome Genome-Wide Association Studies

2025-03-27

Abstract excerpt

<title>Abstract</title> <p>Advancements in large-scale analysis of metabolites in human peripheral blood samples revealed the links between metabolite concentrations and genetic variations. This field is known as metabolome-genome-wide association study (MGWAS). Although MGWAS is a powerful tool, it has some limitations, particularly in terms of the number of metabolites that can be measured. Whether the observed...

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Literature Corpus work: ee614de3-0221-5ea6-ba8a-7f645ec548ea
DOI: 10.21203/rs.3.rs-5590960/v1

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