Article

Differential metabolic activity and discovery of therapeutic targets using summarized metabolic pathway models

2018-07-11

Abstract excerpt

<h4>Background</h4> in spite of the increasing availability of genomic and transcriptomic data, there is still a gap between the detection of perturbations in gene expression and the understanding of their contribution to the molecular mechanisms that ultimately account for the phenotype studied. Alterations in the metabolism are behind the initiation and progression of many diseases, including cancer. The wealth...

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Literature Corpus work: 5e1c6f7d-006b-5e04-ba17-f2acae0767ef
DOI: 10.1101/367334

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