Article

KDM4B down-regulates ERα signaling independent on its demethylase activity in vascular calcification

2023-06-28

Abstract excerpt

<h4>Aims: </h4>: Vascular Calcification (VC) is recognized as an independent predictor of cardiovascular events. Estrogen replacement was reported as protective treatment against vascular calcification in postmenopausal women, while it is controversial because of its potential carcinogenicity. ERα co-regulators have been putatively considered as potential therapeutic targets for ERα-related cancers. However, the m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ee3532e8-8e4e-5a0e-915e-dd5540b199c5
DOI: 10.21203/rs.3.rs-3063847/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

KDM4B down-regulates ERα signaling independent on its demethylase activity in vascular calcificationDOI 10.21203/rs.3.rs-3063847/v1Read

KDM4B modulates ERα signaling pathway to participate in vascular smooth muscle cell calcificationSemantic proximity Read

Roles of Histone Acetylation Modifiers and Other Epigenetic Regulators in Vascular CalcificationSemantic proximity Read

Histone Lysine Methylation Modification and Its Role in Vascular CalcificationSemantic proximity Read

An ncBAF-ETS2 Chromatin-Remodelling Axis Drives Vascular Smooth Muscle Cell Osteogenic Reprogramming in Vascular CalcificationSemantic proximity Read

Cdon suppresses Vascular Smooth Muscle Calcification via Repression of Wnt/Runx2 axisSemantic proximity Read

Epigenetic Reader Bromodomain-Containing Protein 4 in Aging-Related Vascular Pathologies and Diseases: Molecular Basis, Functional Relevance, and Clinical PotentialSemantic proximity Read

The Epigenetic Landscape of Vascular Calcification: An Integrative PerspectiveSemantic proximity Read

Regulation of MDM2 E3 ligase-dependent vascular calcification by MSX1/2.Semantic proximity Read

KAP1 modulates osteogenic differentiation via the ERK/Runx2 cascade in vascular smooth muscle cellsSemantic proximity Read

NEAT1 regulates VSMC differentiation and calcification in as long noncoding RNA NEAT1 enhances phenotypic and osteogenic switching of vascular smooth muscle cells in atherosclerosis via scaffolding EZH2.Semantic proximity Read

NEXN protects against vascular calcification by promoting SERCA2 SUMOylation and stabilizationSemantic proximity Read

Identification of miR136, miR155, and miR183 in vascular calcification in human peripheral arteriesSemantic proximity Read