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The Epigenetic Landscape of Vascular Calcification: An Integrative Perspective

1 Feb 2020

Abstract excerpt

Vascular calcification (VC) is an important complication among patients of advanced age, those with chronic kidney disease, and those with diabetes mellitus. The pathophysiology of VC encompasses passive occurrence of physico-chemical calcium deposition, active cellular secretion of osteoid matrix upon exposure to metabolically noxious stimuli, or a variable combination of both processes. Epigenetic alterations...

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PMID: 32024140
DOI: 10.3390/ijms21030980

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