Article

14-3-3ζ constrains insulin secretion by regulating mitochondrial function in pancreatic β-cells

2021-10-17

Abstract excerpt

While critical for neurotransmitter synthesis in the brain, members of the 14-3-3 protein family are often assumed to have redundant, over-lapping roles due to their high sequence homology and ubiquitous expression. Despite this assumption, various mammalian 14-3-3 isoforms have now been implicated in regulating cellular and organismal metabolism; however, these functions were primarily observed in cell lines or f...

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Literature Corpus work: ee1e5777-1dd9-554a-8eae-7a51948d3dc1
DOI: 10.1101/2021.10.17.464702

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