THE MAJOR ROLE OF JUNCTIONAL DIVERSITY IN THE HORSE ANTIBODY REPERTOIRE

Abstract excerpt

The sequencing of the antibody repertoire (Rep-seq) revolutionized the diversity of antigen B cell receptor studies, allowing deep and quantitative analysis to decipher the role of adaptive immunity in health and disease. Particularly, horse ( Equus caballus ) polyclonal antibodies have been produced and used since the century XIX to treat and prophylaxis of diphtheria, tuberculosis, tetanus, pneumonia, and, more...

Topics

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• Bacteriophages and microbial interactions
• High-Throughput Nucleotide Sequencing
• Immunoglobulin Heavy Chains
• Immunoglobulin Light Chains
• Monoclonal and Polyclonal Antibodies Research
• RNA and protein synthesis mechanisms
• T-cell and B-cell Immunology
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

ee191f1a-4f5c-59e2-b653-e6372b4b3303

DOI

10.1101/2022.06.20.496904