Article
Structural and genetic diversity in antibody repertoires from diverse species.
Current opinion in structural biology - 1 Aug 2015
de los Rios Miguel, Criscitiello Michael F, Smider Vaughn V
Abstract excerpt
The antibody repertoire is the fundamental unit that enables development of antigen specific adaptive immune responses against pathogens. Different species have developed diverse genetic and structural strategies to create their respective antibody repertoires. Here we review the shark, chicken, camel, and cow repertoires as unique examples of structural and genetic diversity. Given the enormous importance of...
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