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Article

Nuclear receptor DHR4 controls the timing of steroid hormone pulses during Drosophila development.

PLoS biology - 1 Sept 2011

Ou Qiuxiang, Magico Adam, King-Jones Kirst

Abstract excerpt

In insects, precisely timed periodic pulses of the molting hormone ecdysone control major developmental transitions such as molts and metamorphosis. The synthesis and release of ecdysone, a steroid hormone, is itself controlled by PTTH (prothoracicotopic hormone). PTTH transcript levels oscillate with an 8 h rhythm, but its significance regarding the timing of ecdysone pulses is unclear. PTTH acts on its target...

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Identifiers

PMID: 21980261
DOI: 10.1371/journal.pbio.1001160
PMCID: PMC3181225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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