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Article

Drosophila hormone receptor 38 functions in metamorphosis: a role in adult cuticle formation.

Genetics - 1 Jul 1998

Kozlova T, Pokholkova G V, Tzertzinis G, Sutherland J D, Zhimulev I F, Kafatos F C

Abstract excerpt

DHR38 is a member of the steroid receptor superfamily in Drosophila homologous to the vertebrate NGFI-B-type orphan receptors. In addition to binding to specific response elements as a monomer, DHR38 interacts with the USP component of the ecdysone receptor complex in vitro, in yeast and in a cell line, suggesting that DHR38 might modulate ecdysone-triggered signals in the fly. We characterized the molecular...

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Identifiers

PMID: 9649534
DOI: 10.1093/genetics/149.3.1465
PMCID: PMC1460226

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