Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isoform-specific regulation of a steroid hormone nuclear receptor by an E3 ubiquitin ligase in Drosophila melanogaster.

Genetics - 1 Nov 2011

Gradilla Ana-Citlali, Mansilla Alicia, Ferrús Alberto

Abstract excerpt

The steroid hormone 20-hydroxyecdysone (20E) regulates gene transcription through the heterodimeric nuclear receptor composed of ecdysone receptor (EcR) and Ultraspiracle (USP). The EcR gene encodes three protein isoforms--A, B1, and B2--with variant N-terminal domains that mediate tissue and developmental stage-specific responses to 20E. Ariadne-1a is a conserved member of the RING finger family of ubiquitin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Active Transport, Cell Nucleus
Share to Ecdysone
Share to Metamorphosis, Biological

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Protein Isoforms

Share to Receptors, Steroid

Share to Single-Cell Analysis

Share to Ubiquitin-Protein Ligases

Share to Ubiquitination

Source

Open in PubMed Open full text

Identifiers

PMID: 21900267
DOI: 10.1534/genetics.111.132191
PMCID: PMC3213379

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isoform-specific regulation of a steroid hormone nuclear receptor by an E3 ubiquitin ligase in Drosophila melanogaster.PMID 21900267Read ↗

Ecdysone signaling in adult Drosophila melanogaster.Semantic proximity Read ↗

Opportunistic binding of EcR to open chromatin drives tissue-specific developmental responsesSemantic proximity Read ↗

The dual role of ultraspiracle, the Drosophila retinoid X receptor, in the ecdysone response.Semantic proximity Read ↗

The genomic response to 20-hydroxyecdysone at the onset of Drosophila metamorphosis.Semantic proximity Read ↗

Analysis of transcriptional activity mediated by Drosophila melanogaster ecdysone receptor isoforms in a heterologous cell culture system.Semantic proximity Read ↗

Ubiquitination of nuclear receptorsSemantic proximity Read ↗

SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development.Semantic proximity Read ↗

Rapid divergence of the ecdysone receptor in Diptera and Lepidoptera suggests coevolution between ECR and USP-RXR.Semantic proximity Read ↗

Sox14 is required for transcriptional and developmental responses to 20-hydroxyecdysone at the onset of drosophila metamorphosis.Semantic proximity Read ↗

Genetic control of specificity to steroid-triggered responses in Drosophila.Semantic proximity Read ↗

CDK8-Cyclin C Mediates Nutritional Regulation of Developmental Transitions through the Ecdysone Receptor in Drosophila.Semantic proximity Read ↗

Drosophila hormone receptor 38 functions in metamorphosis: a role in adult cuticle formation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.