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Article

The genomic response to 20-hydroxyecdysone at the onset of Drosophila metamorphosis.

Genome biology - 1 Jan 2005

Beckstead Robert B, Lam Geanette, Thummel Carl S

Abstract excerpt

BACKGROUND: The steroid hormone 20-hydroxyecdysone (20E) triggers the major developmental transitions in Drosophila, including molting and metamorphosis, and provides a model system for defining the developmental and molecular mechanisms of steroid signaling. 20E acts via a heterodimer of two nuclear receptors, the ecdysone receptor (EcR) and Ultraspiracle, to directly regulate target gene transcription. RESULTS:...

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Identifiers

PMID: 16356271
DOI: 10.1186/gb-2005-6-12-r99
PMCID: PMC1414087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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