Article
SWI/SNF component BAF250a coordinates OCT4 and WNT signaling pathway to control cardiac lineage differentiation
2019-01-18
Abstract excerpt
Dissecting epigenetic mechanisms controlling early cardiac differentiation will provide insights into heart regeneration and heart disease treatment. SWI/SNF complexes remodel nucleosomes to regulate gene expression and play a key role in organogenesis. Here we reported a unique function of BAF250a in regulating the physical interaction of OCT4 and β-CATENIN during cardiac lineage differentiation from human ESCs....
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Identifiers and source
- Literature Corpus work
- edc929f6-f77d-5fb2-9005-3f4c9100abb4
- DOI
- 10.1101/524454