Article
BAF200 is required for heart morphogenesis and coronary artery development.
PloS one - 1 Jan 2014
He Lingjuan, Tian Xueying, Zhang Hui, Hu Tianyuan, Huang Xiuzhen, Zhang Libo, Wang Zhong, Zhou Bin
Abstract excerpt
ATP-dependent SWI/SNF chromatin remodeling complexes utilize ATP hydrolysis to non-covalently change nucleosome-DNA interactions and are essential in stem cell development, organogenesis, and tumorigenesis. Biochemical studies show that SWI/SNF in mammalian cells can be divided into two subcomple...
Topics
- Animals
- Cell Differentiation
- Cell Movement
- Chromosomal Proteins, Non-Histone
- Coronary Vessels
- Embryonic Development
- Endothelial Cells
- Heart
- Mice
- Mice, Inbred C57BL
- Mutation
- Myocardium
- Neovascularization, Physiologic
- Organogenesis
- Transcription Factors