Article

Population-level genome sequencing reveals distinct Mycobacterium tuberculosis intrahost mutational trajectories in simian immunodeficiency virus co-infected and antiretroviral treated non-human primates

2026-04-04

Abstract excerpt

Whole genome sequencing of Mycobacterium tuberculosis (Mtb) populations from clinical samples has increasingly identified genes undergoing selection within and between hosts that drive differential infection and treatment outcomes. However, the intrahost Mtb mutational landscape—especially in the context of human immunodeficiency virus coinfection and antiretroviral therapy (ART)—remains less clear, as do the pot...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ed75cb8e-793c-5689-bd32-5398ed4a58cc
DOI: 10.64898/2026.04.03.714442

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Population-level genome sequencing reveals distinct Mycobacterium tuberculosis intrahost mutational trajectories in simian immunodeficiency virus co-infected and antiretroviral treated non-human primatesDOI 10.64898/2026.04.03.714442Read

Population-level genome sequencing reveals distinct Mycobacterium tuberculosis intrahost mutational trajectories in simian immunodeficiency virus-coinfected and antiretroviral treated non-human primates.Semantic proximity Read

Genomic diversity in autopsy samples reveals within-host dissemination of HIV-associated Mycobacterium tuberculosis.Semantic proximity Read

The Nature and Evolution of Genomic Diversity in the Mycobacterium tuberculosis Complex.Semantic proximity Read

In-host population dynamics of Mycobacterium tuberculosis complex during active disease.Semantic proximity Read

Diversity of Mycobacterium tuberculosis across evolutionary scalesSemantic proximity Read

In-host population dynamics of M. tuberculosis during treatment failureSemantic proximity Read

Within-host pathogen population diversity predicts treatment response in TuberculosisSemantic proximity Read

Diversity of Mycobacterium tuberculosis across Evolutionary Scales.Semantic proximity Read

Direct transmission of within-host Mycobacterium tuberculosis diversity to secondary cases can lead to variable between-host heterogeneity without de novo mutation: A genomic investigationSemantic proximity Read

Human tuberculosis and Mycobacterium tuberculosis complex: A review on genetic diversity, pathogenesis and omics approaches in host biomarkers discovery.Semantic proximity Read

Multiplexed strain phenotyping defines consequences of genetic diversity in Mycobacterium tuberculosis for infection and vaccination outcomesSemantic proximity Read

Understanding Mycobacterium tuberculosis through its genomic diversity and evolutionSemantic proximity Read