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Understanding Mycobacterium tuberculosis through its genomic diversity and evolution

28 Feb 2025

Abstract excerpt

Pathogen evolution and genomic diversity are shaped by specific host immune pressures and therapeutic interventions. Analysis of the extant genomes of circulating strains of Mycobacterium tuberculosis, a leading cause of infectious mortality that has co-evolved with humans for thousands of years, can provide new insights into host-pathogen interactions that underlie specific aspects of pathogenesis and onward...

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PMID: 40019877
DOI: 10.1371/journal.ppat.1012956

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