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Article

Genomic diversity in autopsy samples reveals within-host dissemination of HIV-associated Mycobacterium tuberculosis.

Nature medicine - 1 Dec 2016

Lieberman Tami D, Wilson Douglas, Misra Reshma, Xiong Lealia L, Moodley Prashini, Cohen Ted, Kishony Roy

Abstract excerpt

Mycobacterium tuberculosis remains a leading cause of death worldwide, especially among individuals infected with HIV. Whereas phylogenetic analysis has revealed M. tuberculosis spread throughout history and in local outbreaks, much less is understood about its dissemination within the body. Here we report genomic analysis of 2,693 samples collected post mortem from lung and extrapulmonary biopsies of 44 subjects...

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Identifiers

PMID: 27798613
DOI: 10.1038/nm.4205
PMCID: PMC5508070

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Source receipt: pubmed, retrieved 7 Sept 2026.

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