Article

Using combined RNA/DNA short read sequencing to investigate allele-specific expression from the inactive X chromosome in human cells

2026-05-24

Abstract excerpt

<h4>ABSTRACT</h4> Many genomic regions exhibit allele-specific expression. This effect is most pronounced in imprinted genes, where one copy of a gene is epigenetically silenced, and the inactive X chromosome of female cells, where almost the entire chromosome is silenced. Allele specific gene expression can have significant effects on human health and is implicated in a wide array of diseases. Research into alle...

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Literature Corpus work: ed5765db-62b0-5dc2-af5c-59f0681df904
DOI: 10.64898/2026.05.21.726886

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