Article

XDec Simplex Map of Breast Cancer Cell States Enables Precise Modeling and Targeting of Breast Cancer

2022-07-07

Abstract excerpt

<h4>SUMMARY</h4> The characterization of cancer cell states within the tumor microenvironment is a key to understanding tumor biology and an important step toward the development of precision therapies. To reconstruct this information from bulk RNA-seq profiles, we developed the XDec Simplex Mapping (XDec-SM) approach, a reference-optional deconvolution method that leverages single-cell information, when such inf...

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Literature Corpus work: ed56d82a-d342-5be8-8b17-d24b5d00f111
DOI: 10.1101/2022.07.06.498858

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